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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
23.64
Human Site:
T255
Identified Species:
43.33
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
T255
V
T
S
T
Q
Q
Q
T
R
I
S
A
S
S
A
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
T253
V
T
S
T
Q
Q
Q
T
R
I
S
A
S
S
A
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
T261
V
T
S
T
Q
Q
Q
T
R
I
S
A
S
S
A
Dog
Lupus familis
XP_543425
664
72715
T266
V
T
S
S
Q
Q
Q
T
R
I
S
A
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
T255
V
T
S
S
Q
Q
Q
T
R
I
S
A
S
S
A
Rat
Rattus norvegicus
Q66H76
586
64001
V246
L
E
D
V
R
P
S
V
E
S
L
L
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
T256
V
N
A
S
Q
Q
Q
T
R
I
S
A
S
S
A
Frog
Xenopus laevis
Q2TCH4
506
55983
T216
P
G
H
L
E
V
K
T
N
Q
V
N
S
D
E
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
A129
A
S
P
G
S
G
S
A
G
P
V
I
K
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
H243
A
V
P
G
Q
Q
V
H
Q
A
Y
T
S
Q
A
Honey Bee
Apis mellifera
XP_624308
559
62451
Q240
N
S
S
S
H
Q
H
Q
T
V
T
D
S
P
Y
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
K123
I
R
A
S
S
S
R
K
S
L
G
P
P
S
Q
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
P338
Q
P
Q
I
S
Q
P
P
L
R
T
A
S
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
N.A.
80
13.3
0
N.A.
26.6
20
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
93.3
26.6
6.6
N.A.
33.3
46.6
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
0
0
0
0
8
0
8
0
54
0
0
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
8
8
8
0
% D
% Glu:
0
8
0
0
8
0
0
0
8
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
16
0
8
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
8
0
8
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
47
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% K
% Leu:
8
0
0
8
0
0
0
0
8
8
8
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
8
8
16
0
0
8
8
8
0
8
0
8
8
16
0
% P
% Gln:
8
0
8
0
54
70
47
8
8
8
0
0
0
8
8
% Q
% Arg:
0
8
0
0
8
0
8
0
47
8
0
0
0
0
0
% R
% Ser:
0
16
47
39
24
8
16
0
8
8
47
0
77
62
0
% S
% Thr:
0
39
0
24
0
0
0
54
8
0
16
8
0
0
0
% T
% Val:
47
8
0
8
0
8
8
8
0
8
16
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _